Amorolfine

Amorolfine, Antifungal

Under the treatment of fungal infections of the nail, it is useful to prescribe antifungal premises, such as amorolfine. In addition, for skin fungus, it is possible to prescribe azoles for local use. Many preparations on the basis of azoles exist, with a low skin absorption, and therefore a significant distribution in the body. They are used against fungal infections of the skin caused by dermatophytes, or yeast. The secondary effects are exceptional. Other preparations, in the form of an ovum, are very effective against vaginal candidiasis. The "varnish" : There are galenical formulations, in the form of film solutions, or "varnish", which are specially adapted to the treatment of fungal infections of the nails. Side effects are also exceptional. Thus, Amorolfine blocks the synthesis of ergosterol by enzymatic action on two levels. It has great persistence and allows a weekly treatment. It is important to grind up the sick part before applying the Amorolfine.

Amorolfine: treatment of onychomycosis

The onychomycoses due to dermatophytes require first a lapped of the finger, either mechanical, chisel, lime, either chemical, potassium iodide. Then apply a local antifungal under occlusive bandage. If several nails are reached, taking additional antifungal by general way is recommended. If no hyperkeratosis under the nails, you just try to apply on the sick nail, a film solution in a weekly way of Amorolfine until complete cure. A complementary treatment with a systemic antifungal is sometimes useful in cases of multiple lesions.

Amorolfine: inhibitor of ergosterol

For the treatment of fungal infections of the nail, some imidazole antifungals different from the amorolfine, are used locally in the form of dermatological preparations or ova gynecological (tioconazole and isoconazole). Inhibitor of the last stages of the synthesis of ergosterol : The amoralfine is a derivative of morpholine, therefore chemically different from imidazole derivatives, and triazole, which inhibit enzymes involved in the transformation of zymosterol ergosterol. The Amorolfine opposes itself to the ergosterol biosynthesis of and development of various fungi such as dermaphytes (tricophyton), yeast (candida albicans), and various molds. The amorolfine is a dermatological preparations in the form of varnish.

Amorolfine precautions of use

The amorolfine is packaged in bottles of 125 ml. In case of antecedents of reactions of anaphylaxies to products, it is necessary to consult a doctor before any treatment.Taking amorolfine in the event of pregnancy or breastfeeding should be done under medical supervision. For children or infants, not any application to the skin without medical advice. In case of eye contact, rinse abondament.