Letrozole

Letrozole, Anti estrogen

The letrozole is a non-steroidal estrogen inhibitor of aromatase, which is used in the treatment of hormono dependent breast cancer in women who have reached menopause. Letrozole acts by slowing down the production of oestrogen within the body, at the origin of the development of the breast cancer in women, by blocking the aromatase, the enzyme at the origin of their synthesis.

Létrozole, extended adjuvant treatment

The letrozole is prescribed in extended adjuvant treatment. This means that the duration of treatment with letrozole is superior to the classical 5-year-old duration for a treatment of hormonal origin. This exceptional duration of treatment in the létrozole aims at reducing the risks of recurrence of the breast cancer in menopausal woman. The letrozole is currently the only generic drug prescribed in extended adjuvant treatment, and its long-term effects are still unknown, in the absence of clinical study on this term.

Secondary Effects Létrozole

The secondary effects due to the takaig létrozole are quite rare. They usually occur through hot flashes, articular and muscular pains (aches). In cases of extended adjuvant treatment, it is important to controlling osteoporosis, and bone mineral density. In the case of family history related to cholesterol, regular medical follow-up is necessary. More rarely, migraines, water retention provoking the enflement of diverse parts of the body, a weighty taking, a state of general tireness, nausea and stomach upsets, disorders of the digestive system, urticaria, sweating problems, may appear, as well as visual perception disorders. Most of secondary effects of letrozole which were observed are very slight, and did lead in very rare opportunities to discontinuation of therapy. If these symptoms suggestive side effects for the duration of a treatment to letrozole, It is advisable to contact her own doctor.